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Preventing pandemic risks from dual-use research

A new organisation working with governments and aid agencies to shift international development funding toward the most cost-effective programs — making “best buys” the default and improving how aid decisions are made.

Idea Summary

Preventing pandemic risks from dual-use research focuses on reducing the chance that scientific research unintentionally contributes to large-scale outbreaks. Some areas of life sciences research can create serious risks if accidents occur or if findings are misapplied. The aim is not to slow down science, but to ensure that research with pandemic potential is handled with appropriate safeguards.

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The approach centers on stronger norms, guidelines, and decision-making within academia and research funding. By working with universities, journals, and funders, this work promotes clearer standards for assessing risks before research is approved, funded, or published. Better oversight helps discourage unnecessarily dangerous research while preserving the benefits of valuable scientific work.

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This is preventative, upstream work with long time horizons. Impact comes from influencing how high-risk decisions are made before harm occurs. When successful, improved safeguards reduce the probability of rare but catastrophic events, generating substantial expected impact even when visible outcomes are limited.

Think you’re a rare fit?

Founder Profile

Ideal founder profile


A founding team combining a respected scientist (e.g., a virologist or biosafety expert) with policy or advocacy experience and a senior policy professional or consultant who has worked on biosecurity or global health policy. Both have a proven ability to publish or communicate persuasively, build partnerships with academics and regulators, and maintain credibility in international settings. They approach the work as neutral, evidence‑driven advocates and are sensitive to the ethical and political risks of DURC.

 

Key traits and experience

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  • Scientific credibility: Experts emphasise that credibility is crucial when influencing the biosafety sector. The ideal co‑founding team should include people with an academic or medical background (e.g. virology, biosafety, medicine) and an understanding of dual‑use research.

  • Policy or advocacy experience: In addition to technical expertise, the team needs experience in policy, consulting or advocacy to navigate academic and government systems effectively.

  • Track record and alliances: Successful founders will have a strong professional track record and the ability to build alliances with academic institutions, think‑tanks and leading researchers. This experience helps them gain access to key decision‑makers and counters scepticism toward “outsiders”. Years of experience and credible partnerships are seen as a prerequisite.

  • Non‑partisan, international perception: The organisation must be seen as an international, neutral actor. Founders should be comfortable working across borders and cultures, and be able to forge strategic partnerships that enhance credibility and access.

  • Risk awareness and mitigation: The founders need to be keenly aware of the political and information‑hazard risks associated with DURC advocacy and proactively mitigate them.

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Charity Entrepreneurship (CE) is a registered charity in England and Wales (Charity Number 1195850). CE supports its incubated charities through a fiscal sponsorship with Players Philanthropy Fund (Federal Tax ID: 27-6601178, ppf.org/pp), a Maryland charitable trust with federal tax-exempt status as a public charity under Section 501(c)(3) of the Internal Revenue Code.


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